The evidence

    These sources describe the need. They aren't results for Protocols itself, which still needs product-specific testing.

    Supplement use is common. Overlap matters.

    60.2% of US adults aged 20+ used a dietary supplement; 38.7% used two or more in the past 30 days.

    CDC / NCHS Data Brief 561, May 2026. NHANES August 2021–August 2023. These figures describe use, not harm or Protocols outcomes.

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    Follow-through can benefit from support.

    Thom et al. reported a 1.08-day between-group improvement in self-reported medication-adherent days per week with primary-care health coaching.

    2015, 12-month trial. Evidence for that coaching intervention, not evidence that Kokorology improves adherence.

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    GLP-1 care needs more than a weight readout.

    The STEP-1 exploratory DXA substudy reported a 9.7% reduction in lean body mass in the semaglutide group at 68 weeks.

    2021; 140 scanned participants. Lean body mass is not the same as skeletal muscle or strength. This does not establish that non-adherence caused the change.

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    Nutrition and movement belong beside clinical care.

    A 2025 multi-society advisory describes nutrition, physical activity and individualised support during GLP-1 treatment.

    Clinical guidance, not a trial of Protocols. Medication and treatment decisions remain with the prescriber.

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    Guides and resources